Identification of true drug response to antidepressants. Use of pattern analysis.

  title={Identification of true drug response to antidepressants. Use of pattern analysis.},
  author={Frederic M. Quitkin and Judith Godwin Rabkin and Donald C. Ross and Jonathan W. Stewart},
  journal={Archives of general psychiatry},
  volume={41 8},
The purpose of this study was to develop a method for differentiating specific ("true") and nonspecific antidepressant drug response for the individual patient. Patterns of clinical response, based on weekly global ratings of clinical status, were generated for each of 185 patients participating in six-week placebo-controlled drug trials. We hypothesized and found that substantially more patients receiving active than placebo medication displayed treatment response patterns characterized both… CONTINUE READING

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