Identification of transforming genes of subgroup A and C strains of Herpesvirus saimiri.

@article{Jung1991IdentificationOT,
  title={Identification of transforming genes of subgroup A and C strains of Herpesvirus saimiri.},
  author={Jae U Jung and John J. Trimble and Norval W. King and Brigitte Biesinger and Burkhard Fleckenstein and Ronald C Desrosiers},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1991},
  volume={88 16},
  pages={7051-5}
}
Herpesvirus saimiri is an oncogenic herpesvirus that induces rapidly progressing lymphomas in New World primates. Using retrovirus vectors for gene transfer, specific open reading frames of H. saimiri were tested for their ability to transform rodent cells in culture. One open reading frame, designated STP-C488 (for saimiri-transformation-associated protein of the subgroup C strain 488), phenotypically transformed Rat-1 cells, resulting in formation of foci, growth at reduced serum… CONTINUE READING

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