Identification of transcription factor binding sites derived from transposable element sequences using ChIP-seq.
@article{Conley2010IdentificationOT, title={Identification of transcription factor binding sites derived from transposable element sequences using ChIP-seq.}, author={Andrew B. Conley and I. King Jordan}, journal={Methods in molecular biology}, year={2010}, volume={674}, pages={ 225-40 } }
Transposable elements (TEs) form a substantial fraction of the non-coding DNA of many eukaryotic genomes. There are numerous examples of TEs being exapted for regulatory function by the host, many of which were identified through their high conservation. However, given that TEs are often the youngest part of a genome and typically exhibit a high turnover, conservation-based methods will fail to identify lineage- or species-specific exaptations. ChIP-seq has become a very popular and effective…
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