Identification of tissue inhibitor of metalloproteinases-1 (TIMP-1) in human teeth and its distribution in cementum and dentine.

@article{Ishiguro1994IdentificationOT,
  title={Identification of tissue inhibitor of metalloproteinases-1 (TIMP-1) in human teeth and its distribution in cementum and dentine.},
  author={Koich Ishiguro and Kazuo Yamashita and Haruo Nakagaki and Kazushi Iwata and Takao Hayakawa},
  journal={Archives of oral biology},
  year={1994},
  volume={39 4},
  pages={345-9}
}
An inhibitory activity toward matrix metalloproteinases such as interstitial collagenase, 72-kDa gelatinase/type IV collagenase, and stromelysin-1 was detected in an EDTA extract of pulverized roots of human teeth, and identified as TIMP-1 by sodium dodecyl sulphate-polyacrylamide gel electrophoresis and immunoblotting. Distribution of TIMP-1 in human… CONTINUE READING