Identification of three major synovial lining cell populations by monoclonal antibodies directed to Ia antigens and antigens associated with monocytes/macrophages and fibroblasts.

@article{Burmester1983IdentificationOT,
  title={Identification of three major synovial lining cell populations by monoclonal antibodies directed to Ia antigens and antigens associated with monocytes/macrophages and fibroblasts.},
  author={Gerd ‐ R{\"u}diger Burmester and Alexandra Dimitriu-Bona and S. J. Waters and Robert J. Winchester},
  journal={Scandinavian journal of immunology},
  year={1983},
  volume={17 1},
  pages={69-82}
}
Synovial lining cells obtained from patients with rheumatoid arthritis or non-inflammatory joint diseases were divisible into three populations according to the expression of surface antigens detected by various monoclonal antibodies. A population of cells designated type I was defined by the presence of Ia antigens. Fc receptors, five different monocyte lineage differentiation antigens, and the property of phagocytosis. The greatly increased amounts of both Ia antigens and certain monocyte… CONTINUE READING

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