Identification of the vesicular nucleotide transporter (VNUT) in taste cells.

  title={Identification of the vesicular nucleotide transporter (VNUT) in taste cells.},
  author={Ken Iwatsuki and Reiko Ichikawa and Miki Hiasa and Yoshinori Moriyama and Kunio Torii and Hisayuki Uneyama},
  journal={Biochemical and biophysical research communications},
  volume={388 1},
Taste cells are chemosensory epithelial cells that sense distinct taste qualities. It is the type II taste cell that express G-protein coupled receptors to sense either umami, sweet, or bitter compounds. Whereas several reports have suggested involvement of ATP in taste signal transduction, there is a paucity of molecular information about how ATP is stored and being released. The recent discovery of a novel vesicular nucleotide transporter (VNUT) led us to examine whether VNUT exist in the… CONTINUE READING

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