Identification of the topology and functional domains of PAQR10.

@article{Jin2012IdentificationOT,
  title={Identification of the topology and functional domains of PAQR10.},
  author={Ting Jin and Daqian Xu and Qiurong Ding and Yi-xuan Zhang and Chenqian Mao and Yi Pan and Zhenzhen Wang and Yan Chen},
  journal={The Biochemical journal},
  year={2012},
  volume={443 3},
  pages={643-53}
}
PAQR10 (progestin and adipoQ receptor 10) is a Golgi-localized protein that is able to enhance the retention and activation of Ras proteins in the Golgi apparatus, subsequently leading to a sustained ERK (extracellular-signal-regulated kinase) signalling. However, little is known about the topology and functional domains of PAQR10. In the present study, we extensively dissected and analysed the structure of PAQR10. The topology analysis reveals that PAQR10 is an integral membrane protein with… CONTINUE READING

Citations

Publications citing this paper.

Similar Papers

Loading similar papers…