Identification of the satA gene encoding a streptogramin A acetyltransferase in Enterococcus faecium BM4145.

@article{RendeFournier1993IdentificationOT,
  title={Identification of the satA gene encoding a streptogramin A acetyltransferase in Enterococcus faecium BM4145.},
  author={Rosanna Rende-Fournier and Roland Leclercq and Marc Galimand and J P Duval and Patrice Courvalin},
  journal={Antimicrobial agents and chemotherapy},
  year={1993},
  volume={37 10},
  pages={2119-25}
}
Enterococcus faecium BM4145, a clinical isolate from urine, was resistant to streptogramin group A antibiotics by inactivation. The strain harbored a plasmid containing a gene, satA, responsible for this resistance; this gene was cloned and sequenced. It encoded SatA, a protein deduced to be 23,634 Da in mass and homologous with a new family of chloramphenicol acetyltransferases described in Agrobacterium tumefaciens, Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. The… CONTINUE READING

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