Identification of the rat adrenal zona fasciculata/reticularis specific protein, inner zone antigen (IZAg), as the putative membrane progesterone receptor.

@article{Raza2001IdentificationOT,
  title={Identification of the rat adrenal zona fasciculata/reticularis specific protein, inner zone antigen (IZAg), as the putative membrane progesterone receptor.},
  author={Farah S Raza and Hiroshi Takemori and Hiromasa Tojo and Mitsuhiro Okamoto and Gavin P. Vinson},
  journal={European journal of biochemistry},
  year={2001},
  volume={268 7},
  pages={2141-7}
}
Using immunological methods, a protein specific to the inner zones of the rat adrenal cortex, and called inner zone antigen (IZAg), was previously shown to have two interrelated forms of 26 kDa (IZAg1) and 55-60 kDa (IZAg2), and to have an action on steroid hydroxylation. After two-dimensional gel electrophoresis, and immunoaffinity column purification, N-terminal amino-acid analysis showed that the first 12 amino acids were identical to those of a recently described putative membrane located… CONTINUE READING