Identification of the pathogenic pathways in osteoarthritic hip cartilage: commonality and discord between hip and knee OA.

Abstract

OBJECTIVE To define for the first time the transcriptomes of normal and end-stage osteoarthritis (OA) hip cartilage. MATERIALS AND METHODS RNA was isolated from cartilage within 2h of joint replacement surgery. Gene expression was analyzed using Agilent GeneSpring GX 11 following hybridization to Illumina Human HT-12 V3 microarrays. Real-time reverse… (More)
DOI: 10.1016/j.joca.2012.05.006

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