Identification of the origin of double minutes in normal human cells by laser-based chromosome microdissection approach

Abstract

Single copies of tiny chromosome fragments, appearing as double minutes, were observed in a high proportion of cells from amniotic fluid cultures of two mothers undergoing prenatal testing because of advanced age. We applied a laser-based chromosome microdissection method to diagnose the origin of the double minutes. The diagnostic procedures consisted of… (More)
DOI: 10.1007/BF00214184

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@article{RajcanSeparovic1995IdentificationOT, title={Identification of the origin of double minutes in normal human cells by laser-based chromosome microdissection approach}, author={Evica Rajcan-Separovic and Hung-Shu Wang and Marsha D. Speevak and Lynn Janes and R. G. Korneluk and Kyo Wakasa and Joh-E. Ikeda}, journal={Human Genetics}, year={1995}, volume={96}, pages={39-43} }