Identification of the novel narrow-spectrum beta-lactamase SCO-1 in Acinetobacter spp. from Argentina.

@article{Poirel2007IdentificationOT,
  title={Identification of the novel narrow-spectrum beta-lactamase SCO-1 in Acinetobacter spp. from Argentina.},
  author={Laurent Poirel and St{\'e}phane Corvec and Melina J Rapoport and Pauline D. Mugnier and Alejandro Petroni and Fernando G. Pasteran and Diego F Faccone and Marcelo F. Galas and Henri Bernard Drugeon and Vincent Cattoir and Patrice L. Nordmann},
  journal={Antimicrobial agents and chemotherapy},
  year={2007},
  volume={51 6},
  pages={2179-84}
}
By studying the beta-lactamase content of several Acinetobacter spp. isolates from Argentina, producing the expanded-spectrum beta-lactamases (ESBL) VEB-1a or PER-2, a novel Ambler class A beta-lactamase gene was identified. It encoded the narrow-spectrum beta-lactamase SCO-1, whose activity was inhibited by clavulanic acid. SCO-1 hydrolyzes penicillins at a high level and cephalosporins and carbapenems at a very low level. beta-Lactamase SCO-1 was identified from unrelated VEB-1a-positive or… CONTINUE READING

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References

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Showing 1-10 of 28 references

More oxacillinases conferring carbapenem resistance in Argentina: first report of OXA-58 in Acinetobacter in the Americas, abstr. C2-112

  • F. Pasterán, M. Rapoport, +5 authors M. Galas
  • Abstr. 45th Intersci. Conf. Antimicrob. Agents…
  • 2005
Highly Influential
7 Excerpts

Molecular cloning: a laboratory manual, 2nd ed

  • J. Sambrook, E. F. Fritsch, T. Maniatis
  • 1989
Highly Influential
9 Excerpts

Plasmid content analysis of the Acinetobacter spp. isolates

  • K. E. Nelson, C. Weinel, +21 authors D. FIG
  • Table 1. VOL
  • 2007
1 Excerpt

More oxacillinases conferring carbapenem resistance in Argentina : first report of OXA - 58 in Acinetobacter in the Americas , abstr . C 2112 . Abstr . 45 th Intersci . Conf . Antimicrob

  • A. Petroni, D. Faccone, +5 authors V. Cagnoni
  • 2006

- mediated antibiotic resistance in Acinetobacter

  • L. Poirel, T. Lambert, P. Nordmann
  • 2005

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