Identification of the intersubunit binding region in rat tyrosine hydroxylase.


Limited proteolysis converts the 39200 molecular weight catalytic domain of rat tyrosine hydroxylase to a monomer with a molecular weight of 37600. The purified monomer is almost fully active, with minor changes in kinetic parameters at pH 7. Mass spectral analysis and N-terminal sequencing of the proteolytically generated species establish that 20 amino… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.