Identification of the hemangioblast in postnatal life.

@article{Pelosi2002IdentificationOT,
  title={Identification of the hemangioblast in postnatal life.},
  author={Elvira Pelosi and Mauro Valtieri and Simona Coppola and R. F. Botta and Marco Gabbianelli and Valentina Lulli and Giovanna Marziali and Barbara Masella and Robert M{\"u}ller and Cecilia Sgadari and Giuseppina Bonanno and Cesare Peschle},
  journal={Blood},
  year={2002},
  volume={100 9},
  pages={3203-8}
}
Postnatal CD34(+) cells expressing vascular endothelial growth factor receptor 2 (KDR) generate hematopoietic or endothelial progeny in different in vitro and in vivo assays. Hypothetically, CD34(+)KDR(+) cells may comprise hemangioblasts bipotent for both lineages. This hypothesis is consistent with 2 series of experiments. In the first series, in clonogenic culture permissive for hematopoietic and endothelial cell growth, CD34(+)KDR(+) cells generate large hemato-endothelial (Hem-End… CONTINUE READING

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