Identification of the heart as the critical site of adenosine mediated embryo protection

@inproceedings{Wendler2010IdentificationOT,
  title={Identification of the heart as the critical site of adenosine mediated embryo protection},
  author={Christopher C. Wendler and Ryan R. Poulsen and Satish K Ghatpande and Robert W Greene and Scott A. Rivkees},
  booktitle={BMC Developmental Biology},
  year={2010}
}
Our understanding of the mechanisms that protect the developing embryo from intrauterine stress is limited. Recently, adenosine has been demonstrated to play a critical role in protecting the embryo against hypoxia via adenosine A1 receptors (A1ARs), which are expressed in the heart, nervous system, and other sites during development. However, the sites of A1AR action that mediate embryo protection are not known. To determine if the heart is a key site of adenosine-mediated embryo protection… CONTINUE READING

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