Identification of the gene for Nance-Horan syndrome (NHS).

BACKGROUND The disease intervals for Nance-Horan syndrome (NHS [MIM 302350]) and X linked congenital cataract (CXN) overlap on Xp22. OBJECTIVE To identify the gene or genes responsible for these diseases. METHODS Families with NHS were ascertained. The refined locus for CXN was used to focus the search for candidate genes, which were screened by… CONTINUE READING