Identification of the estrogen receptor GPER in neoplastic and non-neoplastic human testes

@inproceedings{Rago2011IdentificationOT,
  title={Identification of the estrogen receptor GPER in neoplastic and non-neoplastic human testes},
  author={Vittoria Rago and F. T. Rom{\'e}o and Francesca Giordano and Marcello Maggiolini and Amalia Carpino},
  booktitle={Reproductive biology and endocrinology : RB&E},
  year={2011}
}
BACKGROUND Estrogen signaling is mediated by estrogen receptor beta isoforms in normal and neoplastic human testes. Recently, a G-protein-coupled-receptor (GPER) has been suggested as being involved in rapid responses to estrogens in different normal and tumor cells. METHODS This study investigated the GPER expression in paraffin-embedded samples from non neoplastic and neoplastic human testes (sex-cord stromal and germ cell tumors) by immunohistochemical and Western Blot analyses. RESULTS… CONTINUE READING

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