Identification of the death zone: a spatially restricted region for programmed cell death that sculpts the fly eye

@article{Monserrate2007IdentificationOT,
  title={Identification of the death zone: a spatially restricted region for programmed cell death that sculpts the fly eye},
  author={Jessica P. Monserrate and Carrie Baker Brachmann},
  journal={Cell Death and Differentiation},
  year={2007},
  volume={14},
  pages={209-217}
}
Programmed cell death (PCD) sculpts many developing tissues. The final patterning step of the Drosophila retina is the elimination, through PCD, of a subset of interommatidial lattice cells during pupation. It is not understood how this process is spatially regulated to ensure that cells die in the proper positions. To address this, we observed PCD of lattice cells in the pupal retina in real time. This live-visualization method demonstrates that lattice cell apoptosis is a highly specific… CONTINUE READING

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