Identification of the Vibrio cholerae type 4 prepilin peptidase required for cholera toxin secretion and pilus formation.

@article{Marsh1998IdentificationOT,
  title={Identification of the Vibrio cholerae type 4 prepilin peptidase required for cholera toxin secretion and pilus formation.},
  author={J. W. Marsh and Ronald Keith Taylor},
  journal={Molecular microbiology},
  year={1998},
  volume={29 6},
  pages={
          1481-92
        }
}
Cholera toxin secretion is dependent upon the extracellular protein secretion apparatus encoded by the eps gene locus of Vibrio cholerae. Although the eps gene locus encodes several type four prepilin-like proteins, the peptidase responsible for processing these proteins has not been identified. This report describes the identification of a prepilin peptidase from the V. cholerae genomic database by virtue of its homology with the PilD prepilin peptidase of Pseudomonas aeruginosa. Plasmid… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 36 CITATIONS

Type II secretion and pathogenesis.

  • Infection and immunity
  • 2001
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

DNA-uptake machinery of naturally competent Vibrio cholerae.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2013
VIEW 2 EXCERPTS
CITES BACKGROUND