Identification of the Same Na+-Specific DNAzyme Motif from Two In Vitro Selections Under Different Conditions

Abstract

We report an investigation of the functional relationship between two independently selected RNA-cleaving DNAzymes, NaA43, and Ce13, through in vitro selection. The NaA43 DNAzyme was obtained through a combination of gel-based and column-based in vitro selection in the presence of Na+ and reported to be highly selective for Na+ over other metal ions. The… (More)
DOI: 10.1007/s00239-015-9715-7

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