Identification of ten KB425796-A congeners from Paenibacillus sp. 530603 using an antifungal assay against Aspergillus fumigatus in combination with micafungin

@article{Kai2013IdentificationOT,
  title={Identification of ten KB425796-A congeners from Paenibacillus sp. 530603 using an antifungal assay against Aspergillus fumigatus in combination with micafungin},
  author={Hirohito Kai and Midori Yamashita and Shigehiro Takase and Michizane Hashimoto and Hideyuki Muramatsu and Ikuko Nakamura and Koji Yoshikawa and Ryuichi Kanasaki and Masami Ezaki and Kumiko Nitta and Masato Watanabe and Noriaki Inamura and Akihiko Fujie},
  journal={The Journal of Antibiotics},
  year={2013},
  volume={66},
  pages={473-478}
}
The discovery and characterization of natural congeners is one approach for understanding the relationship between chemical structure and biological function. We recently isolated the novel antifungal metabolite KB425796-A produced by the recently isolated bacterium Paenibacillus sp. 530603. On the basis of morphological changes of Aspergillus fumigatus induced by KB425796-A in combination with micafungin, we developed a highly sensitive screening method for the specific detection of KB425796-A… 
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The novel antifungal macrocyclic lipopeptidolactone, KB425796-A (1), was isolated from the fermentation broth of bacterial strain 530603, which was identified as a new Paenibacillus species based on
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