Identification of temporal patterns of gene expression in the uteri of immature, ovariectomized mice following exposure to ethynylestradiol.

@article{Fertuck2003IdentificationOT,
  title={Identification of temporal patterns of gene expression in the uteri of immature, ovariectomized mice following exposure to ethynylestradiol.},
  author={Kirsten C Fertuck and J. E. Eckel and C. Gennings and Timothy R. Zacharewski},
  journal={Physiological genomics},
  year={2003},
  volume={15 2},
  pages={127-41}
}
Estrogen induction of uterine wet weight provides an excellent model to investigate relationships between changes in global gene expression and well-characterized physiological responses. In this study, time course microarray GeneChip data were analyzed using a novel approach to identify temporal changes in uterine gene expression following treatment of immature ovariectomized C57BL/6 mice with 0.1 mg/kg 17alpha-ethynylestradiol. Functional gene annotation information from public databases… CONTINUE READING