Identification of target antigen for SLA/LP autoantibodies in autoimmune hepatitis.

@article{Wies2000IdentificationOT,
  title={Identification of target antigen for SLA/LP autoantibodies in autoimmune hepatitis.},
  author={Ingrid Wies and Silvia Brunner and J{\"u}rgen Henninger and Johannes Herkel and Stephan Kanzler and Karl H Meyer Zum B{\"u}schenfelde and Ansgar Wilhelm Lohse},
  journal={Lancet},
  year={2000},
  volume={355 9214},
  pages={1510-5}
}
BACKGROUND Autoantibodies are a hallmark of autoimmune hepatitis, but most are not disease specific. Autoantibodies to soluble liver antigen (SLA) and to liver and pancreas antigen (LP) have been described as disease specific, occurring in about 30% of all patients with autoimmune hepatitis, but no standardised assays are available. Methods We tested 2000 serum samples from patients with various liver diseases and controls for SLA autoantibodies by inhibition ELISA. Serum samples positive for… CONTINUE READING