Identification of synthetic by-products in combinatorial libraries using high performance liquid chromatography-electrospray ionization mass spectrometry.

@article{Aubagnac1999IdentificationOS,
  title={Identification of synthetic by-products in combinatorial libraries using high performance liquid chromatography-electrospray ionization mass spectrometry.},
  author={J L Aubagnac and Muriel Amblard and Christine Enjalbal and Gilles Subra and Jean Martinez and Philippe Durand and Patrice Renaut},
  journal={Combinatorial chemistry & high throughput screening},
  year={1999},
  volume={2 5},
  pages={
          289-96
        }
}
High performance liquid chromatography (HPLC), electrospray ionization mass spectrometry (ESI) and high performance liquid chromatography coupled to mass spectrometry (LC-MS) were used to analyze randomly chosen samples from parallel syntheses carried out on derivatized polypropylene crowns compatible with a Multipin solid support system. Side-reactions and… CONTINUE READING