Identification of several clades of novel single-stranded circular DNA viruses with conserved stem-loop structures in pig feces

@article{Cheung2014IdentificationOS,
  title={Identification of several clades of novel single-stranded circular DNA viruses with conserved stem-loop structures in pig feces},
  author={A. Cheung and T. Ng and K. Lager and D. Alt and E. Delwart and R. Pogranichniy},
  journal={Archives of Virology},
  year={2014},
  volume={160},
  pages={353-358}
}
  • A. Cheung, T. Ng, +3 authors R. Pogranichniy
  • Published 2014
  • Biology, Medicine
  • Archives of Virology
  • Metagenomic analysis of fecal samples collected from diarrheal swine detected sequences encoding a replication initiator protein (Rep). The genomes of ten novel single-stranded DNA viruses were determined, and they exhibited a similar genome organization. The two putative open reading frames (ORFs) encoding Rep and the capsid protein are bidirectionally transcribed and separated by two intergenic regions. Stem-loop structure(s) typical of genomes that undergo the rolling-circle DNA replication… CONTINUE READING
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