Identification of secretion determinants of the Bordetella pertussis BrkA autotransporter.

  title={Identification of secretion determinants of the Bordetella pertussis BrkA autotransporter.},
  author={David C. Oliver and George Huang and R. Castillo Fernandez},
  journal={Journal of bacteriology},
  volume={185 2},
The autotransporters comprise a functionally diverse family of gram-negative proteins that mediate their own export across the bacterial outer membrane. They consist of an amino-terminal passenger region called the "alpha-domain" and the structural hallmark of the autotransporter family, a carboxy-terminal transporter region usually referred to as the "beta-domain." The passenger region can be quite diverse and constitutes the effector functions of these proteins, whereas the C-terminal region… CONTINUE READING


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