Identification of replication-competent HSV-1 Cgal+ strain signaling targets in human hepatoma cells by functional organelle proteomics.

@article{Santamara2009IdentificationOR,
  title={Identification of replication-competent HSV-1 Cgal+ strain signaling targets in human hepatoma cells by functional organelle proteomics.},
  author={Enrique Santamar{\'i}a and Mar{\'i}a Isabel Mora and Corinne Potel and Joaqu{\'i}n Fern{\'a}ndez-Irigoyen and Elvira Carro-Rold{\'a}n and Rub{\'e}n Hern{\'a}ndez-Alcoceba and Jes{\'u}s Prieto and Alberto Luis Epstein and Fernando Jos{\'e} Corrales},
  journal={Molecular & cellular proteomics : MCP},
  year={2009},
  volume={8 4},
  pages={805-15}
}
In the present work, we have attempted a comprehensive analysis of cytosolic and microsomal proteomes to elucidate the signaling pathways impaired in human hepatoma (Huh7) cells upon herpes simplex virus type 1 (HSV-1; Cgal(+)) infection. Using a combination of differential in-gel electrophoresis and nano liquid chromatography/tandem mass spectrometry, 18 spots corresponding to 16 unique deregulated cellular proteins were unambiguously identified, which were involved in the regulation of… CONTINUE READING
Highly Cited
This paper has 25 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Similar Papers

Loading similar papers…