Identification of rare variants in Alzheimer’s disease

  title={Identification of rare variants in Alzheimer’s disease},
  author={Jenny Lord and Alexander J. Lu and Carlos Cruchaga},
  booktitle={Front. Genet.},
Much progress has been made in recent years in identifying genes involved in the risk of developing Alzheimer's disease (AD), the most common form of dementia. Yet despite the identification of over 20 disease associated loci, mainly through genome wide association studies (GWAS), a large proportion of the genetic component of the disorder remains unexplained. Recent evidence from the AD field, as with other complex diseases, suggests a large proportion of this "missing heritability" may be due… CONTINUE READING
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Identification of rare variants in Alzheimer’s disease

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