Identification of rare pathogenic bacteria in a clinical microbiology laboratory: impact of matrix-assisted laser desorption ionization-time of flight mass spectrometry.

@article{Seng2013IdentificationOR,
  title={Identification of rare pathogenic bacteria in a clinical microbiology laboratory: impact of matrix-assisted laser desorption ionization-time of flight mass spectrometry.},
  author={Piseth Seng and C{\'e}dric Abat and Jean Marc Rolain and Philippe Colson and Jean-Christophe Lagier and Fr{\'e}d{\'e}rique Gouriet and Pierre Edouard Fournier and Michel Drancourt and Bernard La Scola and Didier Raoult},
  journal={Journal of clinical microbiology},
  year={2013},
  volume={51 7},
  pages={2182-94}
}
During the past 5 years, matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry (MS) has become a powerful tool for routine identification in many clinical laboratories. We analyzed our 11-year experience in routine identification of clinical isolates (40 months using MALDI-TOF MS and 91 months using conventional phenotypic identification [CPI]). Among the 286,842 clonal isolates, 284,899 isolates of 459 species were identified. The remaining 1,951 isolates… CONTINUE READING
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