Identification of quorum-sensing regulated proteins in the opportunistic pathogen Pseudomonas aeruginosa by proteomics.

@article{ArvaloFerro2003IdentificationOQ,
  title={Identification of quorum-sensing regulated proteins in the opportunistic pathogen Pseudomonas aeruginosa by proteomics.},
  author={Catalina Ar{\'e}valo-Ferro and Morten Hentzer and Gerold Reil and Angelika G{\"o}rg and Staffan J. Kjelleberg and Michael C Givskov and Kathrin 4 Riedel and Leo Eberl},
  journal={Environmental microbiology},
  year={2003},
  volume={5 12},
  pages={1350-69}
}
The Gram-negative bacterium Pseudomonas aeruginosa is an opportunistic human pathogen which is responsible for severe nosocomial infections in immunocompromised patients and is the major pathogen in cystic fibrosis. The bacterium utilizes two interrelated quorum-sensing (QS) systems, which rely on N-acyl-homoserine lactone (AHL) signal molecules, to control the expression of virulence factors and biofilm development. In this study, we compared the protein patterns of the intracellular… CONTINUE READING
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