Identification of quantitative trait loci involved in contextual and auditory-cued fear conditioning in BXD recombinant inbred strains.

@article{Owen1997IdentificationOQ,
  title={Identification of quantitative trait loci involved in contextual and auditory-cued fear conditioning in BXD recombinant inbred strains.},
  author={E H Owen and Steven C. Christensen and Richard E Paylor and Jeanne M. Wehner},
  journal={Behavioral neuroscience},
  year={1997},
  volume={111 2},
  pages={292-300}
}
Fear conditioning shows associations formed between contextual or auditory stimuli with an unconditioned stimulus. Inbred mouse strains differ in their ability to demonstrate fear conditioning, suggesting at least a partial genetic influence. The present study identified the possible chromosomal loci regulating fear conditioning in BXD recombinant inbred strains using quantitative trait loci (QTL) analysis. Estimates of heritability for all 3 measures of conditioning were about .28… CONTINUE READING