Identification of putative active site residues of ACAT enzymes.

Abstract

In this report, we sought to determine the putative active site residues of ACAT enzymes. For experimental purposes, a particular region of the C-terminal end of the ACAT protein was selected as the putative active site domain due to its high degree of sequence conservation from yeast to humans. Because ACAT enzymes have an intrinsic thioesterase activity… (More)
DOI: 10.1194/jlr.M800131-JLR200

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