Identification of proteins encoded by the L1 and L2 open reading frames of human papillomavirus 1a.

@article{Doorbar1987IdentificationOP,
  title={Identification of proteins encoded by the L1 and L2 open reading frames of human papillomavirus 1a.},
  author={John Doorbar and Phillip H. Gallimore},
  journal={Journal of virology},
  year={1987},
  volume={61 9},
  pages={2793-9}
}
The human papillomavirus 1 (HPV-1) virion is composed of two virally encoded proteins: a 57,000-molecular-weight polypeptide (57K polypeptide), which is the product of the L1 open reading frame (ORF), and a 78K polypeptide, which is derived from the L2 ORF. The 57K (L1) product, which represents the major structural component, appears to be disulfide cross-linked in virus particles. The 78K (L2) protein is a minor component of the virion and does not appear to be disulfide linked either to the… CONTINUE READING