Identification of protein complexes by comparative analysis of yeast and bacterial protein interaction data

Abstract

Mounting evidence shows that many protein complexes are conserved in evolution. Here we use conservation to find complexes that are common to yeast <i>S. Cerevisiae</i> and bacteria <i>H. pylori</i>. Our analysis combines protein interaction data, that are available for each of the two species, and orthology information based on protein sequence comparison… (More)
DOI: 10.1145/974614.974652

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@article{Sharan2004IdentificationOP, title={Identification of protein complexes by comparative analysis of yeast and bacterial protein interaction data}, author={Roded Sharan and Trey Ideker and Brian P. Kelley and Ron Shamir and Richard M. Karp}, journal={Journal of computational biology : a journal of computational molecular cell biology}, year={2004}, volume={12 6}, pages={835-46} }