Identification of protein antigens associated with the nuclear matrix and with clusters of interchromatin granules in both interphase and mitotic cells.

@article{Turner1987IdentificationOP,
  title={Identification of protein antigens associated with the nuclear matrix and with clusters of interchromatin granules in both interphase and mitotic cells.},
  author={Bryan M. Turner and Lisa Franchi},
  journal={Journal of cell science},
  year={1987},
  volume={87 ( Pt 2)},
  pages={269-82}
}
Monoclonal antibody 3C5 recognizes a family of protein antigens present predominantly within the nucleus of interphase cells. We have shown previously that the epitope recognized by 3C5 is phosphorylated and have concluded that the proteins defined by this antibody share a common phosphorylation site. Using a combination of immunofluorescence microscopy and immunogold labelling in conjunction with electron microscopy, we have studied the distribution of 3C5-reactive material within interphase… CONTINUE READING

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