Identification of prostate-enriched proteins by in-depth proteomic analyses of expressed prostatic secretions in urine.

@article{Principe2012IdentificationOP,
  title={Identification of prostate-enriched proteins by in-depth proteomic analyses of expressed prostatic secretions in urine.},
  author={Simona Principe and Yunee Kim and Simona Fontana and Vladimir Ignatchenko and Julius O Nyalwidhe and Raymond S Lance and Dean A. Troyer and Riccardo Alessandro and O. John Semmes and Thomas Kislinger and Richard S. Drake and Jeffrey A. Medin},
  journal={Journal of proteome research},
  year={2012},
  volume={11 4},
  pages={2386-96}
}
Urinary expressed prostatic secretion or "EPS-urine" is proximal tissue fluid that is collected after a digital rectal exam (DRE). EPS-urine is a rich source of prostate-derived proteins that can be used for biomarker discovery for prostate cancer (PCa) and other prostatic diseases. We previously conducted a comprehensive proteome analysis of direct expressed prostatic secretions (EPS). In the current study, we defined the proteome of EPS-urine employing Multidimensional Protein Identification… CONTINUE READING

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