Identification of propafenone metaboliser phenotype from plasma and urine excretion data


The aim of the study was to validate a test based on analyses of urine to identify the propafenone metaboliser phenotype during routine chronic therapy. Twenty seven patients chronically treated with propafenone were studied. A debrisoquine test was performed in 10. Propafenone and its metabolites in plasma and urine were measured by HPLC. Propafenone, 5… (More)
DOI: 10.1007/BF00314930


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