Identification of promoter elements involved in cell-specific regulation of rat smooth muscle myosin heavy chain gene transcription.

@article{White1996IdentificationOP,
  title={Identification of promoter elements involved in cell-specific regulation of rat smooth muscle myosin heavy chain gene transcription.},
  author={Sheryl L. White and Robert B. Low},
  journal={The Journal of biological chemistry},
  year={1996},
  volume={271 25},
  pages={
          15008-17
        }
}
In order to identify cis-acting regulatory elements involved in smooth muscle cell-specific gene regulation, we have cloned a 4. 7-kilobase pair fragment of the promoter for the rat smooth muscle myosin heavy chain, a protein expressed in differentiated smooth muscle cells. Sequence analysis of a 1.7-kilobase pair portion of this clone reveals potential binding sites for known transcription factors. A comparison of the primary sequence between the rat and rabbit smooth muscle myosin heavy chain… CONTINUE READING
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