Identification of polymorphisms in ultraconserved elements (UCEs) associated with clinical outcomes in patients (pts) with stage II/III colorectal cancer (CRC).

Abstract

3529 Background: Recent studies have not demonstrated therapeutic advances in pts with stage II-III CRC indicating the need for novel methodology. UCEs are non-coding sequences with 100% sequence identity among orthologous genomic regions of human and murine species. UCEs harbor critical biologic functions including splicing, epigenetics, and… (More)

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