Identification of polymorphism at the glutathione S-transferase, GSTM3 locus: evidence for linkage with GSTM1*A.

@article{Inskip1995IdentificationOP,
  title={Identification of polymorphism at the glutathione S-transferase, GSTM3 locus: evidence for linkage with GSTM1*A.},
  author={A Inskip and J Elexperu-Camiruaga and Neil Buxton and Palitha S Dias and Josephine MacIntosh and Douglas L. Campbell and Peter Wyn Jones and L Yengi and J A Talbot and Richard C. Strange},
  journal={The Biochemical journal},
  year={1995},
  volume={312 ( Pt 3)},
  pages={713-6}
}
Allelism in the glutathione S-transferase, GSTM3 gene has been identified using PCR with specific primers to exon 6/exon 7. Sequencing showed the mutant GSTM3*B allele to have a three-base deletion in intron 6 with a frequency of 0.158. The mutation generates a recognition sequence, 5'-AAGATA-3', for the negative transcription factor YY1. GSTM3*B was significantly associated with GSTM1*A.