Identification of plasma microRNA-21 as a biomarker for early detection and chemosensitivity of non–small cell lung cancer

@inproceedings{Wei2011IdentificationOP,
  title={Identification of plasma microRNA-21 as a biomarker for early detection and chemosensitivity of non–small cell lung cancer},
  author={Juan Wei and Wen Gao and Cheng-jun Zhu and Yi-qian Liu and Zhu Mei and Ting Cheng and Yongqian Shu},
  booktitle={Chinese journal of cancer},
  year={2011}
}
Studies have shown cell-free microRNA (miRNA) circulating in the serum and plasma with specific expression in cancer, indicating the potential of using miRNAs as biomarkers for cancer diagnosis and therapy. This study was to investigate whether plasma miRNA-21 (miR-21) can be used as a biomarker for the early detection of non-small cell lung cancer (NSCLC) and to explore its association with clinicopathologic features and sensitivity to platinum-based chemotherapy. We used real-time RT-PCR to… CONTINUE READING