Identification of photooxidation sites in bovine alpha-crystallin.

@article{Finley1997IdentificationOP,
  title={Identification of photooxidation sites in bovine alpha-crystallin.},
  author={E L Finley and Mark Busman and James W. Dillon and Rosalie K. Crouch and Kevin L. Schey},
  journal={Photochemistry and photobiology},
  year={1997},
  volume={66 5},
  pages={635-41}
}
Because UV irradiation of proteins can produce reactive oxygen species and exposure to UV light has been implicated in cataractogenesis, the sites of photooxidation of bovine alpha-crystallin, a major lens protein with molecular chaperone activity, were identified using tandem mass spectrometry (MS/MS). Bovine alpha-crystallin was irradiated with UV light (> 293 nm) for 1, 4 and 8 h, digested with trypsin and analyzed by matrix-assisted laser desorption ionization, time-of-flight mass… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

Similar Papers

Loading similar papers…