Identification of peptide oxidation by tandem mass spectrometry.

@article{Schey2000IdentificationOP,
  title={Identification of peptide oxidation by tandem mass spectrometry.},
  author={Kevin L. Schey and E L Finley},
  journal={Accounts of chemical research},
  year={2000},
  volume={33 5},
  pages={299-306}
}
Oxidative reactions play important roles in a variety of biochemical events ranging from normal metabolism to aging and disease processes. Proteins represent major targets for modification in these reactions, and identification of sites and structures of modifications may lead to mechanistic understanding and approaches for prevention. In this Account, the utility of mass spectrometry and its advantages are described for the identification of oxidative modifications to protein targets. A… CONTINUE READING

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