Identification of oxalic acid and tartaric acid as major persistent pain-inducing toxins in the stinging hairs of the nettle, Urtica thunbergiana.

  title={Identification of oxalic acid and tartaric acid as major persistent pain-inducing toxins in the stinging hairs of the nettle, Urtica thunbergiana.},
  author={Han-Yi Fu and Shiang-Jiuun Chen and Ruei-Feng Chen and Wang-Hsien Ding and Ling-Long Kuo-Huang and Rong‐Nan Huang},
  journal={Annals of botany},
  volume={98 1},
BACKGROUND AND AIMS Once human skin contacts stinging hairs of Urtica spp. (stinging nettles), the irritant is released and produces pain, wheals or a stinging sensation which may last for >12 h. However, the existence of pain-inducing toxins in the stinging hairs of Urtica thunbergiana has never been systematically demonstrated. Experiments were therefore conducted to identify the persistent pain-inducing agents in the stinging hairs of U. thunbergiana. METHODS The stinging hairs of U… 

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