Identification of novel universal housekeeping genes by statistical analysis of microarray data.

@article{Lee2007IdentificationON,
  title={Identification of novel universal housekeeping genes by statistical analysis of microarray data.},
  author={S. Lee and M. Jo and Jungeun Lee and S. S. Koh and Soyoun Kim},
  journal={Journal of biochemistry and molecular biology},
  year={2007},
  volume={40 2},
  pages={
          226-31
        }
}
  • S. Lee, M. Jo, +2 authors Soyoun Kim
  • Published 2007
  • Biology, Medicine
  • Journal of biochemistry and molecular biology
  • Housekeeping genes are widely used as internal controls in a variety of study types, including real time RT-PCR, microarrays, Northern analysis and RNase protection assays. However, even commonly used housekeeping genes may vary in stability depending on the cell type or disease being studied. Thus, it is necessary to identify additional housekeeping-type genes that show sample-independent stability. Here, we used statistical analysis to examine a large human microarray database, seeking genes… CONTINUE READING
    95 Citations
    Identification of Reference Genes across Physiological States for qRT-PCR through Microarray Meta-Analysis
    • 47
    • PDF
    Validation of reference genes for quantitative expression analysis by real-time RT-PCR in Saccharomyces cerevisiae
    • 368
    • PDF
    Using Ribosomal Protein Genes as Reference: A Tale of Caution
    • 176
    • PDF
    RefGenes: identification of reliable and condition specific reference genes for RT-qPCR data normalization
    • 244
    • PDF
    Human housekeeping genes, revisited.
    • 732

    References

    SHOWING 1-10 OF 22 REFERENCES
    Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • 15,717
    • Highly Influential
    • PDF
    Statistical modeling for selecting housekeeper genes
    • 183
    • PDF
    Housekeeping genes in cancer: normalization of array data.
    • 59
    • PDF
    Selection of optimal internal controls for gene expression profiling of liver disease.
    • Soyoun Kim, Taeuk Kim
    • Biology, Medicine
    • BioTechniques
    • 2003
    • 50
    • PDF
    Housekeeping genes as internal standards: use and limits.
    • 1,431
    • PDF
    Prediction of compound signature using high density gene expression profiling.
    • 253
    • PDF
    Control selection for RNA quantitation.
    • 800
    • Highly Influential
    • PDF
    Expression profiling and identification of novel genes in hepatocellular carcinomas
    • 86
    • PDF
    Functional and genomic implications of global gene expression profiles in cell lines from human hepatocellular cancer
    • 111
    Comparison of human adult and fetal expression and identification of 535 housekeeping/maintenance genes.
    • 522
    • PDF