Identification of novel universal housekeeping genes by statistical analysis of microarray data.

  title={Identification of novel universal housekeeping genes by statistical analysis of microarray data.},
  author={S. Lee and M. Jo and Jungeun Lee and S. S. Koh and Soyoun Kim},
  journal={Journal of biochemistry and molecular biology},
  volume={40 2},
  • S. Lee, M. Jo, +2 authors Soyoun Kim
  • Published 2007
  • Biology, Medicine
  • Journal of biochemistry and molecular biology
  • Housekeeping genes are widely used as internal controls in a variety of study types, including real time RT-PCR, microarrays, Northern analysis and RNase protection assays. However, even commonly used housekeeping genes may vary in stability depending on the cell type or disease being studied. Thus, it is necessary to identify additional housekeeping-type genes that show sample-independent stability. Here, we used statistical analysis to examine a large human microarray database, seeking genes… CONTINUE READING
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