Identification of novel transmembrane proteins in scirrhous-type gastric cancer by the Escherichia coli ampicillin secretion trap (CAST) method: TM9SF3 participates in tumor invasion and serves as a prognostic factor.

@article{Oo2014IdentificationON,
  title={Identification of novel transmembrane proteins in scirrhous-type gastric cancer by the Escherichia coli ampicillin secretion trap (CAST) method: TM9SF3 participates in tumor invasion and serves as a prognostic factor.},
  author={Htoo Zarni Oo and Kazuhiro Sentani and Naoya Sakamoto and Katsuhiro Anami and Yutaka Naito and Takashi Oshima and Kazuyoshi Yanagihara and Naohide Oue and Wataru Yasui},
  journal={Pathobiology : journal of immunopathology, molecular and cellular biology},
  year={2014},
  volume={81 3},
  pages={138-48}
}
OBJECTIVE Scirrhous-type gastric cancer (GC) is highly aggressive and has a poor prognosis due to rapid cancer cell infiltration accompanied by extensive stromal fibrosis. The aim of this study is to identify genes that encode transmembrane proteins frequently expressed in scirrhous-type GC. METHODS We compared Escherichia coli ampicillin secretion trap (CAST) libraries from 2 human scirrhous-type GC tissues with a normal stomach CAST library. By sequencing 2,880 colonies from scirrhous CAST… CONTINUE READING