Identification of novel indicators of cyclosporine A nephrotoxicity in a CD-1 mouse model.

@article{OConnell2011IdentificationON,
  title={Identification of novel indicators of cyclosporine A nephrotoxicity in a CD-1 mouse model.},
  author={S{\'e}in O'Connell and Craig Slattery and Michael P. Ryan and Tara McMorrow},
  journal={Toxicology and applied pharmacology},
  year={2011},
  volume={252 2},
  pages={201-10}
}
The calcineurin inhibitor cyclosporine A (CsA) is a widely used immunosuppressive agent. However, nephrotoxicity is a serious side effect observed in patients which limits clinical use of CsA. CsA nephrotoxicity is associated with tubulointerstitial injury progressing to nephropathy. This is typically diagnosed by invasive renal biopsy and is often only detected when the disease process is well advanced. Therefore identification of novel, early indicators of CsA nephrotoxicity could be… CONTINUE READING
Highly Cited
This paper has 21 citations. REVIEW CITATIONS

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
11 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 11 extracted citations

Similar Papers

Loading similar papers…