Identification of novel hydrazine metabolites by 15N-NMR.

@article{Preece1991IdentificationON,
  title={Identification of novel hydrazine metabolites by 15N-NMR.},
  author={N. Preece and J. Nicholson and J. Timbrell},
  journal={Biochemical pharmacology},
  year={1991},
  volume={41 9},
  pages={
          1319-24
        }
}
15N-NMR has been used to study the metabolism of hydrazine in rats in vivo. Single doses of [15N2]hydrazine (2.0 mmol/kg: 98.6% g atom) were administered to rats and urine collected for 24 hr over ice. A number of metabolites were detected by 15N-NMR analysis of lyophilized urine. Ammonia was detected as a singlet at 0 ppm and unchanged [15N2]hydrazine was present in the urine detectable as a singlet at 32 ppm. Peaks were observed at 107 and 110 ppm which were identified as being due to the… Expand
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