Identification of novel hub genes associated with liver metastasis of gastric cancer.

@article{Chang2009IdentificationON,
  title={Identification of novel hub genes associated with liver metastasis of gastric cancer.},
  author={Wenjun Chang and Liye Ma and Liping Lin and Liqiang Gu and Xiaokang Liu and Hui Cai and Yong-wei Yu and Xiaojie Tan and Yujia Zhai and Xingxing Xu and Minfeng Zhang and Lingling Wu and Hongwei Zhang and Jianguo Hou and Hongyang Wang and Guangwen Cao},
  journal={International journal of cancer},
  year={2009},
  volume={125 12},
  pages={2844-53}
}
Understanding hub genes involved in gastric cancer (GC) metastasis could lead to effective approaches to diagnose and treat cancer metastasis. In this study, 272 differentially expressed genes between synchronous liver metastasis and the paired GC were selected from microarray assays. KEGG pathway analysis indicated that of 13 enriched pathways, 8 were involved in cancer metastasis. Literature-based annotations showed that the differentially expressed genes significantly enriched known… CONTINUE READING
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