Identification of novel homologous microRNA genes in the rhesus macaque genome

@article{Yue2007IdentificationON,
  title={Identification of novel homologous microRNA genes in the rhesus macaque genome},
  author={Junming Yue and Yi Jian Sheng and Kyle E. Orwig},
  journal={BMC Genomics},
  year={2007},
  volume={9},
  pages={8 - 8}
}
BackgroundMicroRNAs (miRNAs) are about 22 nucleotide (nt) endogenous small RNAs that negatively regulate gene expression. They are a recently described class of regulatory molecules that has biological implications for tumorigenesis, development, metabolism and viral diseases. To date, 533 miRNAs have been identified in human. However, only 71 miRNAs have been reported in rhesus macaque. The rhesus is widely used in medical research because of its genetic and physiological similarity to human… CONTINUE READING

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